ICP-MS generally has the highest sensitivity, which can determine more than 70 different elements in a minute.
Because terpenes are somewhat volatile, the Restek team recommends using gas chromatography and advises against using HPLC for terpene analysis.
Headspace is the most common analytical technique for efficiently removing the residual solvents from the complex cannabis extract matrix.
The workhorse approach for pesticide residue analysis involves using gas chromatography and liquid chromatography tandem mass spectrometry (MS/MS) in the ion transition mode.
For potency analysis via HPLC, grinding/homogenization and alcohol extraction is a common sample prep technique for dried flower and extracts.
The introduction of a series of articles focusing on the applications of instruments for different types of chemical analyses.
Using qualified methods, accreditation and proper documentation are all very important in manufacturing CRMs.
Using a certified reference material (CRM) can provide a high level of traceability and accuracy for measurements in the lab.
Internal standards can compensate for sample-prep and instrument variation, working with calibration curves to further improve data quality and validity.
Back-calculated accuracy, a measure of curve fitness, provides an easy method for determining results’ accuracy without performing additional runs.